RT Book, Section A1 Conly, John A2 Hall, Jesse B. A2 Schmidt, Gregory A. A2 Kress, John P. SR Print(0) ID 1107720197 T1 Infectious Complications of Intravascular Access Devices Used in Critical Care T2 Principles of Critical Care, 4e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071738811 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1107720197 RD 2024/04/16 AB Intravascular access device–associated infections may be either local or bacteremic, and the risk of developing an infection varies with the patient population, the type of device, the microbe, and the patient-microbe-device interaction.The status of all indwelling vascular access devices should be reviewed daily by the critical care team, with attention to the duration of placement, appearance of the exit site, and continued clinical indication for the intravascular device.Central venous catheters account for over 90% of all intravascular device–related bacteremias.Most intravascular device–related bacteremias are caused by endogenous skin flora at the catheter insertion site that migrate along the transcutaneous portion of the catheter with subsequent colonization of the catheter tip.Coagulase-negative staphylococci and Staphylococcus aureus account for just over 50% of all intravascular device–related bacteremias, followed in frequency by gram-negative bacilli and yeast.Diagnosis of intravascular device–related infection, either local or bacteremic, is best approached using a combination of clinical and laboratory criteria.Although treatment of central-line infections due to coagulase-negative staphylococci may be successful without catheter removal, infections caused by S aureus necessitate catheter removal.Central intravascular catheter infections are essentially preventable infections. Successful prevention entails attention to a careful needs assessment for the device, careful site selection, maximal barrier precautions and sterile technique on insertion, insertion by the most skilled operators, rigorous catheter-site care, and interrupting the integrity of the system as little as possible.