RT Book, Section A1 Preiser, Jean-Charles A1 Ichai, Carole A2 Hall, Jesse B. A2 Schmidt, Gregory A. A2 Kress, John P. SR Print(0) ID 1107715788 T1 Glycemic Control T2 Principles of Critical Care, 4e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071738811 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1107715788 RD 2024/04/20 AB The physiological regulation of blood glucose involves hormonal and neural mechanisms, resulting in a control of glucose flux across cell membranes.High glucose concentrations are associated with cellular toxicity.Stress hyperglycemia is a marker of severity of illness.Intensive insulin therapy used to tightly control blood sugar was found beneficial in one single-center study, but not in seven independent other prospective trials.Current recommendations advocate a moderate glucose control by insulin therapy.