RT Book, Section A1 Irwin, David A1 Trescot, Andrea A2 Diwan, Sudhir A2 Staats, Peter S. SR Print(0) ID 1107201008 T1 Cryoneuroablation T2 Atlas of Pain Medicine Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071738767 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1107201008 RD 2024/03/29 AB Cryoneuroablation is an interventional technique aimed at temporary destruction of the nerve providing relief of the pain. The origin of this technique lies in the ancient time but modern cryoanalgesia traces its roots to Cooper et al.1 In 1962, they developed a device that used liquid nitrogen circulating through a hollow tube, insulated except at the tip, to achieve a tip temperature of −196,°C. Amoils,2 an ophthalmic surgeon, developed a simpler handheld device in 1967, which used high-pressure carbon dioxide or nitrous oxide and could achieve temperatures of −70°C. Lloyd et al3 coined the term “cryoanalgesia” for its use in pain management. They proposed that this technique was superior to other methods of peripheral nerve destruction, for example, alcohol, phenol, or surgical lesions, because it is not followed by neuritis or neuralgia.