RT Book, Section A1 Kramer, Jeffery A1 Draper, Christine E. A1 Deer, Timothy R. A1 Pope, Jason E. A1 Levy, Robert A1 Grigsby, Eric J. A2 Diwan, Sudhir A2 Staats, Peter S. SR Print(0) ID 1107200438 T1 Dorsal Root Ganglion Stimulation: Anatomy, Physiology, and Potential for Therapeutic Targeting in Chronic Pain T2 Atlas of Pain Medicine Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071738767 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1107200438 RD 2024/03/28 AB Primary sensory neurons (PSNs) process and transmit a multitude of sensory information from the periphery to the central nervous system. In this regard, they are a key component of the initial pathway by which pain (as well as a variety of other sensory information) is transmitted from both peripheral and axial structures to secondary and tertiary order neurons in the central nervous system. In an acute sense, pain transduction serves as a safety mechanism to protect tissues from injury. Classic pain reflexes that result in withdrawal from harmful stimuli protect tissues from damage. Unfortunately, in some cases, these same neurologic pathways can be dramatically altered resulting in the development of chronic neuropathic pain. One component of the sensory nervous system shown to exhibit a number of pathophysiologic changes that may contribute to chronic pain is the dorsal root ganglion (DRG), the home of the primary sensory neuron cell bodies.