RT Book, Section A1 Nguyen, Vinh A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102570060 T1 Antithrombotic Drugs T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102570060 RD 2024/10/05 AB Obstruction of arterial or venous blood flow to vital vessels can have a dramatic impact on mortality and morbidity. Prior to thrombolytic agents, open surgical procedures were preformed to restore vessel patency and preserve vital organs. Antithrombotic agents are currently the mainstay therapy for achieving fibrinolysis during an acute ischemic event. Indications include acute myocardial infarction, ischemic stroke, deep venous thrombosis, pulmonary embolism, limb ischemia, and central line occlusion. Therefore, antithrombotic agents are used to target these blood clots directly using a catheter-directed thrombolysis or a systemic approach to dissolve the existing obstruction.