RT Book, Section A1 Ionescu, Adrian M. A1 Suyderhoud, Johan P. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102569399 T1 Myocardial Contractility T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102569399 RD 2024/04/19 AB The heart is made up of striated muscle of both atria and ventricles, along with the pacemaker and action-potential conducting tissue. The pacemaker cells of the myocardium have a unique, self-excitatory property, which allows myocardial contractility to occur independently of sympathetic or parasympathetic nervous system input. The intercalated discs allow the fast, uniform, and sequential transmission of electrical activity (action potentials) between myocytes to generate an effective cardiac output to perfuse vital tissue.