RT Book, Section A1 Alshaeri, Taghreed A1 David, Marianne D. A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102568760 T1 Cerebral Protection T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102568760 RD 2024/03/29 AB The cerebral metabolic rate of O2 (CMRO2) is 3-3.8 mL/100 mg/min. Cerebral metabolism has two basic components: neuronal activity and cellular integrity. The brain depends on aerobic glucose metabolism; hence, large O2 demand consumes 20% of total body O2 to maintain neuronal activity for adenosine triphosphate (ATP) generation.