RT Book, Section A1 Lopatin, Jonah A1 Jivan, Kuntal A2 Freeman, Brian S. A2 Berger, Jeffrey S. SR Print(0) ID 1102567475 T1 Spinal Anesthesia T2 Anesthesiology Core Review: Part One Basic Exam YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 9780071821377 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1102567475 RD 2024/04/23 AB The epidural space lies between the walls of the vertebral canal and the meninges. The meninges are composed of three distinct layers (dura, arachnoid, and pia mater) that are continuous cephalad with the cranial meninges. Dura mater, the outermost layer, extends from the foramen magnum to S2 in adults where it fuses with the filum terminale. The innermost layer of dura mater is highly vascular and serves as the principal route for elimination of drugs in the epidural and subarachnoid space. The arachnoid mater lies deep in the dura and serves as a tight barrier, separating the spinal cord from the epidural space. A potential space exists between the dura and arachnoid mater. The pia mater is the deepest layer of the spinal meninges and adheres to the spinal cord. The subarachnoid space lies between the arachnoid and pia mater, and contains the cerebrospinal fluid (CSF).