RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Marciniak, Bruno
A1 Dalens, Bernard J.
SR Print(0)
ID 58075919
T1 Metachromatic Leukodystrophy
T2 Syndromes: Rapid Recognition and Perioperative Implications
YR 2006
FD 2006
PB The McGraw-Hill Companies
PP New York, NY
SN 9780071354554
LK accessanesthesiology.mhmedical.com/content.aspx?aid=58075919
RD 2024/04/19
AB Inherited  disorder  of  the  myelin  metabolism  with  progressive  loss  of  white  matter  in  the  central  and  peripheral  nervous  system.  It  is  the  most  common  form  of  leukoencephalopathy  and  is  characterized  by  sulfatide  accumulation  in  the  brain  and  other  areas  of  the  body  (liver,  gall  bladder,  kidneys,  and/or  spleen).  Clinical  manifestations  may  include  seizures,  behavioral  changes,  spasticity,  progressive  dementia,  psychomotor  dysfunction  leading  to  paralysis,  and  visual  impairment  leading  to  blindness.