RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Marciniak, Bruno A1 Dalens, Bernard J. SR Print(0) ID 58075168 T1 Mannosidosis T2 Syndromes: Rapid Recognition and Perioperative Implications YR 2006 FD 2006 PB The McGraw-Hill Companies PP New York, NY SN 9780071354554 LK accessanesthesiology.mhmedical.com/content.aspx?aid=58075168 RD 2024/03/29 AB Lysosomal glycoprotein storage disease with mental retardation, hearing loss, and recurrent infections (upper or lower respiratory tract, and gastrointestinal tract). Other clinical features include coarse face, prominent forehead, prominent jaw, diffuse dysfunction of the brain, severe ataxia, deafness, scoliosis, rheumatoid arthritis, hypotonia, and muscle pain. Two types are described: α and β. α-Mannosidosis displays clinical heterogeneity, ranging from very serious to very mild forms. β-Mannosidosis causes a severe disorder that affects the peripheral and central nervous systems.