RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Marciniak, Bruno A1 Dalens, Bernard J. SR Print(0) ID 58079902 T1 Hereditary Xerocytosis T2 Syndromes: Rapid Recognition and Perioperative Implications YR 2006 FD 2006 PB The McGraw-Hill Companies PP New York, NY SN 9780071354554 LK accessanesthesiology.mhmedical.com/content.aspx?aid=58079902 RD 2024/03/29 AB Hereditary xerocytosis is characterized by red cell membrane abnormality with increased permeability to cations and a greater efflux of potassium than of sodium. Consequently, these red cells lose potassium in excess of sodium gained, with a decrease in total cation content. Osmotically resistant xerocytes result. Clinically, the patient may present with episodes of fatigue, jaundice, pallor, and darkened urine, especially during intense physical activity. At the other end of the spectrum from xerocytosis is hereditary stomatocytosis (or hydrocytosis), in which the red cells are overhydrated and sodium loaded.