RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Marciniak, Bruno
A1 Dalens, Bernard J.
SR Print(0)
ID 58079783
T1 Hereditary Spherocytosis
T2 Syndromes: Rapid Recognition and Perioperative Implications
YR 2006
FD 2006
PB The McGraw-Hill Companies
PP New York, NY
SN 9780071354554
LK accessanesthesiology.mhmedical.com/content.aspx?aid=58079783
RD 2024/04/23
AB Hereditary  spherocytosis  is  characterized  by  a  membrane  defect  within  red  blood  cells  resulting  in  a  shortened  survival  time.  The  red  cells  have  low  amounts  of  lipid  within  the  bilayer  membrane  that  lead  to  an  abnormally  small  amount  of  surface  area.  Because  the  red  blood  cells  are  spherocytic,  flow  through  the  spleen  is  difficult,  resulting  in  hemolysis.  It  is  caused  by  an  inherited  metabolic  defect.