RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Marciniak, Bruno
A1 Dalens, Bernard J.
SR Print(0)
ID 58079188
T1 HARD Syndrome
T2 Syndromes: Rapid Recognition and Perioperative Implications
YR 2006
FD 2006
PB The McGraw-Hill Companies
PP New York, NY
SN 9780071354554
LK accessanesthesiology.mhmedical.com/content.aspx?aid=58079188
RD 2023/12/05
AB HARD  is  an  acronym  for  hydrocephalus,  agyria,  and  retinal  dysplasia.  Very  rare  and  severe  autosomal  recessive  syndrome  quickly  lethal,  with  major  neurologic  impairment.  It  is  characterized  by  type  II  lissencephaly  in  association  with  retinal  dysplasia,  obstructive  hydrocephalus,  and  agenesis  of  the  corpus  callosum.  Affected  infants  typically  have  severe  growth  failure,  severe  microcephaly,  seizures,  microphthalmia,  and  cataracts.