RT Book, Section A1 Vassilakopoulos, Theodoros A2 Tobin, Martin J. SR Print(0) ID 57075391 T1 Chapter 43. Ventilator-Induced Diaphragmatic Dysfunction T2 Principles and Practice of Mechanical Ventilation, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-173626-8 LK accessanesthesiology.mhmedical.com/content.aspx?aid=57075391 RD 2024/04/18 AB Controlled mechanical ventilation (CMV) is a ventilator mode where the respiratory muscles are not contracting, and the ventilator takes full responsibility for inflating the respiratory system. Evidence accumulating over the past two decades has shown that CMV can induce dysfunction of the diaphragm, mainly consisting of atrophy, oxidative stress, and ultrastructural injury, resulting in decreased diaphragmatic contractility. This is called ventilator-induced diaphragmatic dysfunction (VIDD).1