RT Book, Section A1 Pelosi, Paolo A1 Brusasco, Claudia A1 Abreu, Marcelo Gama de A2 Tobin, Martin J. SR Print(0) ID 57068774 T1 Chapter 24. Mechanical Ventilation during General Anesthesia T2 Principles and Practice of Mechanical Ventilation, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-173626-8 LK accessanesthesiology.mhmedical.com/content.aspx?aid=57068774 RD 2024/04/19 AB In the early years following the first demonstration of anesthesia with an inhalation device, different inhalation anesthetic agents were developed and tested in spontaneously breathing subjects. However, the increasing complexity of surgical procedures, the discovery and use of neuromuscular blocking as well as intravenous anesthetic agents, and the need to protect the airways resulted in the need for mechanical ventilation during general anesthesia. Accordingly, anesthesia ventilators were developed to match the particular needs of general anesthesia, which differ from those in other settings, such as the intensive care unit (ICU). Moreover, modern anesthesia is not restricted to the intraoperative period and mechanical ventilation may be required preoperatively and postoperatively.