RT Book, Section
A1 Froese, Alison B.
A1 Ferguson, Niall D.
A2 Tobin, Martin J.
SR Print(0)
ID 57067290
T1 Chapter 19. High-Frequency Ventilation
T2 Principles and Practice of Mechanical Ventilation, 3e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-173626-8
LK accessanesthesiology.mhmedical.com/content.aspx?aid=57067290
RD 2024/04/19
AB High-frequency  ventilation  has  been  an  unconventional  option  for  more  than  three  decades  and  during  that  period  several  varieties  of  high-frequency  ventilators  have  come  and  gone.  Currently,  interest  in  high-frequency  ventilation  in  adult  critical  care  is  part  of  a  larger  search  for  ventilator  strategies  that  can  support  gas  exchange  in  the  severely  hypoxemic  patient  without  contributing  additional  ventilator-induced  lung  injury.  Over  the  past  30  years,  high-frequency  ventilators  provided  an  experimental  tool  that  identified  many  of  the  mechanisms  that  contribute  to  ventilator-induced  lung  injury.  It  became  clear  that  ventilator-induced  lung  injury  is  minimized  by  ventilator  patterns  that  achieve  homogeneous  aeration  of  as  much  of  the  lung  as  possible,  avoiding  both  injury  from  overdistension  (volutrauma)  and  that  arising  from  the  repetitive  opening  and  closing  of  lung  units  in  regions  of  atelectasis  (atelectrauma)  (Fig.  19-1).1  Failure  to  operate  in  the  “safe  zone”  initiates  biotrauma.2,3