RT Book, Section A1 Navalesi, Paolo A1 Maggiore, Salvatore Maurizio A2 Tobin, Martin J. SR Print(0) ID 57063741 T1 Chapter 10. Positive End-Expiratory Pressure T2 Principles and Practice of Mechanical Ventilation, 3e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-173626-8 LK accessanesthesiology.mhmedical.com/content.aspx?aid=57063741 RD 2024/04/20 AB Positive end-expiratory pressure (PEEP) is not a ventilator mode itself, but rather an adjunctive treatment that can be combined with all forms of mechanical ventilation, both controlled and assisted,1–7 or applied to spontaneous breathing throughout the entire respiratory cycle, so-called continuous positive airway pressure (CPAP).8–10 Following the pioneering work of Poulton and Oxon11 and Barach and associates12 who demonstrated in the mid-1930s that application of positive pressure to the airway can effectively treat patients with pulmonary edema, several pathological conditions were proved to benefit from PEEP, which is today considered by intensive care unit physicians as one of the most powerful treatments available for acute respiratory failure (ARF).13