RT Book, Section
A1 Holets, Steven R.
A1 Hubmayr, Rolf D.
A2 Tobin, Martin J.
SR Print(0)
ID 57062093
T1 Chapter 5. Setting the Ventilator
T2 Principles and Practice of Mechanical Ventilation, 3e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-173626-8
LK accessanesthesiology.mhmedical.com/content.aspx?aid=57062093
RD 2024/04/19
AB The  choice  of  ventilator  settings  should  be  guided  by  clearly  defined  therapeutic  end  points.  In  most  instances,  the  primary  goal  of  mechanical  ventilation  is  to  correct  abnormalities  in  arterial  blood-gas  tensions.  In  most  patients,  this  is  accomplished  easily  by  adjusting  the  minute  volume  to  correct  hypercapnia  and  by  treating  hypoxemia  with  oxygen  (O2)  supplementation.  Because  the  volume,  frequency,  and  timing  of  gas  delivered  to  the  lungs  have  important  disease-specific  effects  on  cardiovascular  and  respiratory  systems  functions,  the  physician  must  avoid  simply  managing  the  blood-gas  tensions  of  the  ventilator-dependent  patient.  After  a  brief  review  of  the  capabilities  of  modern  ventilators,  this  chapter  discusses  the  mechanical  determinants  of  patient–ventilator  interactions  and  defines  therapeutic  end  points  in  common  respiratory  failure  syndromes.  These  sections  provide  background  for  the  major  thrust  of  the  chapter,  which  is  to  detail  the  physiologic  consequences  of  positive-pressure  ventilation  and  to  develop  recommendations  for  ventilator  settings  in  various  disease  states  based  on  this  knowledge.