RT Book, Section
A1 Simon, Lee S.
A2 Warfield, Carol A.
A2 Bajwa, Zahid H.
SR Print(0)
ID 3419350
T1 Chapter 61. Nonsteroidal Anti-Inflammatory Drugs
T2 Principles & Practice of Pain Medicine, 2e
YR 2004
FD 2004
PB The McGraw-Hill Companies
PP New York, NY
SN 9780071443494
LK accessanesthesiology.mhmedical.com/content.aspx?aid=3419350
RD 2025/04/21
AB Nonsteroidal  anti-inflammatory  drugs  (NSAIDs)  are  anti-inflammatory,  analgesic,  and  antipyretic  agents.  They  are  used  to  reduce  pain,  decrease  stiffness,  and  improve  function  in  patients  with  osteoarthritis  (OA),  rheumatoid  arthritis  (RA),  and  other  forms  of  arthritis.  They  are  also  used  for  the  treatment  of  pain  including  headache,  dysmenorrhea,  and  postoperative  pain.1–3  Whether  their  effectiveness  is  solely  due  to  their  anti-inflammatory  or  analgesic  effects  or  other  possible  mechanisms  is  not  known.4  There  are  at  least  20  different  NSAIDs  currently  available  in  the  United  States  (Table  61-1).  In  addition,  cyclooxygenase-2  selective  inhibitors  (COX-2  inhibitors,  e.g.,  celecoxib,  rofecoxib),  with  similar  efficacy  but  significantly  decreased  gastrointestinal  (GI)  and  platelet  effects,  are  available.5–8