RT Book, Section A1 Vincent, Jean-Louis A2 Longnecker, David E. A2 Brown, David L. A2 Newman, Mark F. A2 Zapol, Warren M. SR Print(0) ID 56653869 T1 Chapter 80. Hemodynamic Support of the Critically Ill Patient T2 Anesthesiology, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-178513-6 LK accessanesthesiology.mhmedical.com/content.aspx?aid=56653869 RD 2024/03/28 AB Early and adequate resuscitation of patients with acute circulatory failure is important to restore the balance between oxygen needs and delivery. Effective resuscitation can result in improved outcomes.Fluid resuscitation should be guided by repeated fluid challenges.If fluid administration is insufficient to restore an adequate tissue perfusion pressure, vasopressors may be required; norepinephrine is currently considered the best first-line choice.Inotropes or vasodilator drugs may be needed to improve myocardial contractility and cardiac output. Dobutamine remains the inotropic agent of choice.Hemodynamic support should be titrated to the individual patient according to global parameters of hemodynamic and oxygenation status, supported by regional parameters when available.