RT Book, Section A1 Wang, Binbin A1 Kwo, Jean A1 Hellman, Judith A2 Longnecker, David E. A2 Brown, David L. A2 Newman, Mark F. A2 Zapol, Warren M. SR Print(0) ID 56651870 T1 Chapter 74. Evaluation of the Patient with Multiple Organ Dysfunction Syndrome T2 Anesthesiology, 2e YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-178513-6 LK accessanesthesiology.mhmedical.com/content.aspx?aid=56651870 RD 2024/04/20 AB Multiple organ dysfunction syndrome (MODS) is common in critically ill patients and associated with a high mortality rate.There are many underlying etiologies of MODS. In the overall intensive care unit (ICU) population, sepsis is the most common cause of MODS.MODS is characterized by dysfunction of 2 or more organs or systems.Inflammation and microvascular abnormalities are involved in the development of MODS.Therapies for MODS should target the underlying cause, supporting the patient and correcting the physiologic and metabolic derangements caused by dysfunction of the organs and systems.Patients with MODS often require surgery and other invasive procedures.Whenever possible, optimize MODS patients preoperatively.Methods of optimization are dictated by the affected organs and the severity of physiologic and metabolic derangements.