RT Book, Section A1 Sizemore, James M. A1 Cobbs, C. Glenn A1 Carr, Mark B. A2 Hall, Jesse B. A2 Schmidt, Gregory A. A2 Wood, Lawrence D.H. SR Print(0) ID 2291003 T1 Chapter 49. Endocarditis and Other Intravascular Infections T2 Principles of Critical Care, 3e YR 2005 FD 2005 PB The McGraw-Hill Companies PP New York, NY SN 9780071416405 LK accessanesthesiology.mhmedical.com/content.aspx?aid=2291003 RD 2021/03/04 AB The possibility of intravascular infection should be considered in all critically ill patients with bacteremia or fungemia of uncertain origin, particularly when there are known intravascular or endocardial abnormalities or intravascular devices; fever or hemodynamic instability of unclear origin; or signs of inflammation related to an indwelling intravascular device.Blood cultures are the most important diagnostic test for this group of infections because most intravascular infections will result in persistent bacteremia or fungemia.Successful therapy often requires prolonged administration of microbicidal agents plus removal of devices.Certain microbes, including staphylococci, enterococci, aerobic gram-negative bacilli, and yeasts, are especially likely to cause intravascular infectious disease.