RT Book, Section A1 Wu, Christopher L. A1 Williams, Brian A. A2 Hadzic, Admir SR Print(0) ID 3509734 T1 Chapter 75. Effects of Regional Anesthesia & Analgesia on Perioperative Outcome T2 NYSORA Textbook of Regional Anesthesia and Acute Pain Management YR 2007 FD 2007 PB The McGraw-Hill Companies PP New York, NY SN 9780071449069 LK accessanesthesiology.mhmedical.com/content.aspx?aid=3509734 RD 2024/03/28 AB Patients with severe medical conditions who undergo surgery are at a higher risk for perioperative morbidity and mortality. These patients have limited physiologic reserves, which may be overwhelmed by the perioperative stress from the trauma of surgery. The use of perioperative regional anesthesia and analgesia may attenuate detrimental perioperative pathophysiology and potentially diminish the incidence of adverse patient outcomes including mortality and major morbidity.1–4 Because only limited data are available on the effect of perioperative peripheral anesthesia and analgesia, this discussion, like much of the available data, focuses on the perioperative use of neuraxial, particularly epidural, anesthesia and analgesia. Nevertheless, the general concepts behind the benefits of perioperative neuraxial anesthesia and analgesia may ultimately be applicable to peripheral anesthesia and analgesia.