RT Book, Section A1 Benzon, Honorio T. A1 Jabri, Rasha S. A2 Hadzic, Admir SR Print(0) ID 3508793 T1 Chapter 70. Neuraxial Anesthesia & Peripheral Nerve Blocks in Patients on Anticoagulants T2 NYSORA Textbook of Regional Anesthesia and Acute Pain Management YR 2007 FD 2007 PB The McGraw-Hill Companies PP New York, NY SN 9780071449069 LK accessanesthesiology.mhmedical.com/content.aspx?aid=3508793 RD 2024/10/14 AB Intraspinal hematoma is a relatively rare condition resulting from a variety of causes. Its incidence is approximately 0.1 per 100,000 patients per year.1,2 Traumatic causes include lumbar puncture and neuraxial anesthesia as well as a complication of spinal surgery. It is more likely to occur in anticoagulated or thrombocytopenic patients, patients with neoplastic disease, or in those with liver disease or alcoholism.3,4 Spontaneous bleeding is rare but may be seen from a spinal arteriovenous malformation or vertebral hemangioma. Approximately one quarter to one third of all cases are associated with anticoagulation therapy.5,6