RT Book, Section A1 Sala-Blanch, Xavier A1 De Andrés, José A1 Barron, Alton A1 Hobeika, Paul A1 Cohen, Adam A1 Somasundaram, Lakshmanasamy A2 Hadzic, Admir SR Print(0) ID 3507113 T1 Chapter 60. Acute Compartment Syndrome of the Limb: Implications for Regional Anesthesia T2 NYSORA Textbook of Regional Anesthesia and Acute Pain Management YR 2007 FD 2007 PB The McGraw-Hill Companies PP New York, NY SN 9780071449069 LK accessanesthesiology.mhmedical.com/content.aspx?aid=3507113 RD 2024/04/18 AB Compartment syndrome is an orthopedic emergency. It is an acute condition of the limbs in which the pressure of isolated or groups of compartments increases dramatically and limits local soft tissue perfusion to the point of ischemic necrosis. Regional anesthesia may mask the signs and symptoms of compartment syndrome, so practitioners should be alert to patient risk factors, clinical presentation, and management of this potentially limb-threatening condition. The musculoskeletal structures of the limbs are enclosed within compartments created by investing, inelastic sheets of fascia that have a limited ability to expand. These compartments contain skeletal muscles that form the bulk of their contents, along with the neurovascular structures that pass through the compartment. If missed, compartment syndrome1 can be a life- and limb-threatening condition.