RT Book, Section
A1 Freeman, Brian S.
A1 Berger, Jeffrey S.
SR Print(0)
ID 1206855224
T1 Cerebral Metabolism
T2 Anesthesiology Core Review: Part Two ADVANCED Exam, 2nd Edition
YR 2024
FD 2024
PB McGraw Hill
PP New York, NY
SN 9781264285730
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1206855224
RD 2024/10/04
AB The  brain  is  a  major  energy-consuming  organ  in  the  body.  An  adult  human  brain  weighs  about  1500  g,  which  represents  about  2%  of  the  body  weight,  yet  it  consumes  approximately  20%  of  the  total  body  oxygen.  In  children  up  to  age  4,  the  brain  utilizes  about  50%  of  the  total  body  oxygen.  Cerebral  metabolic  rate  (CMR)  is  expressed  in  terms  of  oxygen  consumption  (CMRO2),  which  in  a  normal  conscious  adult  is  approximately  3.5  mL/100  g/min  or  about  50  mL  O2/min  in  the  resting  state.  In  the  absence  of  pathology,  CMR  is  coupled  with  cerebral  blood  flow  (CBF)  at  50  mL/100  g/min.