RT Book, Section A1 Corwin, Howard L. A1 Napolitano, Lena M. A2 Schmidt, Gregory A. A2 Kress, John P. A2 Douglas, Ivor S. SR Print(0) ID 1201807857 T1 Anemia and Red Blood Cell Transfusion in the Critically Ill Patient T2 Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition YR 2023 FD 2023 PB McGraw Hill PP New York, NY SN 9781264264353 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1201807857 RD 2023/12/07 AB KEY POINTSAnemia is common in the critically ill and is associated with the use of red blood cell (RBC) transfusions and worse clinical outcomes.Anemia management, independent of RBC transfusion, is important. This may include the use of erythropoiesis-stimulating agents and/or iron.The risks of RBC transfusions have expanded and are well documented.Little data support efficacy of RBC transfusions in many clinical situations in which they are given.In general for critically ill patients, a restrictive strategy (consider RBC transfusion when hemoglobin ≤7 g/dL) is recommended.In patients with acute coronary syndrome, consider RBC transfusion when Hb ≤8 g/dL.Patient preferences and Patient Blood Management guidelines should be considered when considering blood transfusion.Anemia prevention in the ICU includes efforts to reduce phlebotomy and diagnostic laboratory testing, use of pediatric or low-volume sampling tubes, and blood loss prevention.