RT Book, Section
A1 Al-Hegelan, Mashael
A1 MacIntyre, Neil R.
A2 Schmidt, Gregory A.
A2 Kress, John P.
A2 Douglas, Ivor S.
SR Print(0)
ID 1201803057
T1 Novel Modes of Mechanical Ventilation
T2 Hall, Schmidt and Wood’s Principles of Critical Care, 5<sup>th</sup> Edition
YR 2023
FD 2023
PB McGraw Hill
PP New York, NY
SN 9781264264353
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1201803057
RD 2023/12/07
AB KEY  POINTSMechanical  ventilators  are  support  devices,  not  therapeutic  devices.  The  clinical  goal  is  thus  to  support  gas  exchange  without  causing  harm.A  number  of  challenges  face  clinicians  in  providing  safe  and  effective  mechanical  ventilatory  support.  Three  of  the  most  important  are:  (1)  supporting  gas  exchange  without  causing  injury  from  applied  pressure  or  FiO2;  (2)  providing  comfortable  interactive  support;  (3)  facilitating  the  discontinuation  process  as  the  lung  recovers.Innovations  need  to  focus  on  addressing  clinical  challenges  and  improve  important  clinical  outcomes.Over  the  past  quarter  century,  innovations  that  have  generated  considerable  clinical  interest  include  airway  pressure  release  ventilation,  high-frequency  ventilation,  feedback  controls  on  variable  flow-pressure-targeted  breaths,  proportional  assist  ventilation,  and  neutrally  adjusted  ventilatory  assistance.While  all  of  these  innovations  have  conceptual  appeal  and  supporting  observational  data,  none  as  yet  has  convincing  randomized  control  trial  data,  demonstrating  improved  clinical  outcomes.