RT Book, Section
A1 Doerschug, Kevin C.
A1 Schmidt, Gregory A.
A2 Schmidt, Gregory A.
A2 Kress, John P.
A2 Douglas, Ivor S.
SR Print(0)
ID 1201802981
T1 Patient-Ventilator Synchrony
T2 Hall, Schmidt and Wood’s Principles of Critical Care, 5<sup>th</sup> Edition
YR 2023
FD 2023
PB McGraw Hill
PP New York, NY
SN 9781264264353
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1201802981
RD 2023/11/29
AB KEY  POINTSPatient-ventilator  asynchrony  results  from  an  imbalance  between  a  patient’s  respiratory  drive  and  the  output  from  the  mechanical  ventilator.Patient-ventilator  asynchrony  is  associated  with  poor  patient  outcomes  including  mortality.  Postulated  mechanisms  include  excessive  work  of  breathing  and  lung  overdistension.Ventilator  waveform  analysis  is  a  no-cost  and  easily  employed  method  to  detect  patient-ventilator  asynchrony  and  monitor  the  effectiveness  of  strategies  to  mitigate  asynchronies.Attempts  to  normalize  arterial  blood  gas  values  often  increase  patient-ventilator  asynchrony.Increases  in  set  minute  ventilation—ventilator  overdrive—decrease  respiratory  drive  and  improve  synchrony,  often  with  low  but  acceptable  PaCO2.