RT Book, Section A1 Ingrande, Jerry A1 Pearn, Matthew L. A1 Patel, Hemal H. A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193231126 T1 General Anesthetics and Therapeutic Gases T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1193231126 RD 2024/11/12 AB General anesthetics depress the CNS to a sufficient degree to permit the performance of surgery and unpleasant procedures. General anesthetics have low therapeutic indices and thus require great care in administration. The selection of specific drugs and routes of administration to produce general anesthesia is based on the pharmacokinetic properties and on the secondary effects of the various drugs. The practitioner should consider the context of the proposed diagnostic or surgical procedure and the individual patient’s characteristics and associated medical conditions when choosing appropriate anesthetic agents.