RT Book, Section A1 MacNaughton, Wallace K. A1 Sharkey, Keith A. A2 Brunton, Laurence L. A2 Knollmann, Björn C. SR Print(0) ID 1193238560 T1 Pharmacotherapy of Inflammatory Bowel Disease T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th Edition YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781264258079 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1193238560 RD 2024/10/14 AB AbbreviationsAPC: antigen-presenting cell5-ASA: 5-aminosalicylic acid, mesalamineCNS: central nervous systemCOX: cyclooxygenaseFDA: Food and Drug AdministrationGI: gastrointestinalGPCR: G protein-coupled receptorHGPRT: hypoxanthine-guanine phosphoribosyl transferaseHPA: hypothalamic-pituitary-adrenal (axis)5HT: 5-hydroxytryptamine (serotonin)IBD: inflammatory bowel diseaseIFN: interferonIL: interleukinJAK: Janus kinaseMAO: monoamine oxidase6-MMP: 6-methyl-mercaptopurineNE: norepinephrineNF-κB: nuclear factor-κBNSAID: nonsteroidal anti-inflammatory drugPPAR-γ: peroxisome proliferator-activated receptor gammaS1P: sphingosine-1-phosphateSTAT: signal transducer and activator of transcriptionTB: tuberculosisTGF: transforming growth factorTH: T helper (lymphocyte)TNF: tumor necrosis factorTPMT: thiopurine methyltransferaseTYK2: tyrosine kinase 2XO: xanthine oxidase