RT Book, Section A1 Butterworth IV, John F. A1 Mackey, David C. A1 Wasnick, John D. SR Print(0) ID 1190607272 T1 Anesthesia for Patients with Neurological & Psychiatric Diseases T2 Morgan & Mikhail’s Clinical Anesthesiology, 7e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781260473797 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1190607272 RD 2024/09/13 AB KEY CONCEPTS Induction of anesthesia in patients receiving long-term levodopa therapy may result in either marked hypotension or hypertension. In patients with multiple sclerosis, increases in body temperature cause exacerbation of symptoms. The major risk of anesthesia in patients with autonomic dysfunction is severe hypotension, compromising cerebral and coronary blood flow. Autonomic hyperreflexia should be expected in patients with spinal cord lesions above T6 and can be precipitated by surgical manipulations. The most important interaction between anesthetic agents and tricyclic antidepressants is an exaggerated response to both indirect-acting vasopressors and sympathetic stimulation.