RT Book, Section A1 Voulgarelis, Stylianos A2 Ellinas, Herodotos A2 Matthes, Kai A2 Alrayashi, Walid A2 Bilge, Aykut SR Print(0) ID 1176457305 T1 Vasoactive Medications T2 Clinical Pediatric Anesthesiology YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781259585746 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1176457305 RD 2024/03/28 AB FOCUS POINTSThe increased metabolic rate of children comparing to adults requires a different selection of vasoactive drugs to restore and maintain the oxygen delivery to the tissues and support the circulation during periods of stress or sepsis.Phenylephrine has a very narrow therapeutic spectrum in the pediatric population, mostly limited for patients with tetralogy of Fallot (TOF) and hypertrophic obstructive cardiomyopathy (HOCM)Milrinone is used in pediatric patients with congenital heart disease, cardiomyopathy, and heart failure and in patients with increased pulmonary vascular resistance (PVR).Dopamine is still used to improve tissue perfusion and urine output in neonates and premature infants.Newborn myocardium contractility depends significantly on serum calcium levels. Hypocalcemia needs to be promptly identified and corrected.