RT Book, Section A1 Hall, Stanley M. A1 McDonough, Kathleen H. A2 Levitzky, Michael A2 McDonough, Kathleen A2 Kaye, Alan David A2 Hall, Stanley SR Print(0) ID 1175534032 T1 Hemostasis and Hemotherapy T2 Clinical Physiology in Anesthetic Practice YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781259641954 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1175534032 RD 2024/03/28 AB Hemostasis is the process of preventing the loss of blood when a blood vessel is injured. The platelets or thrombocytes, as discussed in the previous chapter, play an integral role in hemostasis when they are activated and begin clustering together or aggregating. In addition, vasoconstriction of the injured blood vessel decreases blood flow through the injured site such that a clot can form and not be dislodged. Vasoconstriction also decreases the amount of blood that could leak from the injured vessel. The final step in hemostasis is the formation of a permanent clot through activation of the multistep clotting mechanisms involving the formation of interwoven fibrin plugs which trap platelets and blood cells. Eventually scar formation and endothelialization will permanently repair the vessel and the clot will be reabsorbed.