RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164087998 T1 Werner Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164087998 RD 2024/04/23 AB Premature aging disease that begins in adolescence or early adulthood. The early findings, usually within the 20s include loss and graying of hair, hoarseness, and scleroderma-like skin changes, followed by bilateral ocular cataracts, Type 2 diabetes mellitus, hypogonadism, skin ulcers, and osteoporosis in the 30s. Myocardial infarction and cancer are the most common causes of death. The main risks are associated with cardiovascular and neurological complications because of the atheromatous disease. The mean age of death is 54 years.