RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164079764
T1 Myoadenylate Deaminase Deficiency
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164079764
RD 2024/04/18
AB It  is  an  inherited  or  secondarily  acquired  disorder  of  muscle  purine  nucleotide  metabolism.  The  clinical  manifestations  include  exercise-induced  myopathy,  post-exertional  muscle  weakness  or  cramping,  prolonged  fatigue  after  exertion,  and  limping  infant  caused  by  benign  congenital  hypotonia.  Generalized  muscle  pair  is  often  manifested.  There  is  evidence  that  patients  with  myoadenylate  deaminase  deficiency  (and  the  carrier  as  well)  may  be  at  an  increased  risk  of  malignant  hyperthermia  (MH)  when  subjected  to  anesthesia.