RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164078870 T1 Milton Disease T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164078870 RD 2024/04/19 AB It is a disorder of complement regulation in which C1 esterase inhibitor (C1INH), an inhibitor of spontaneous activation of C1, is lacking. This produces circumscribed, nonpitting subepithelial edema involving the lips, eyelids, tongue, larynx, pharynx, respiratory tract, gastrointestinal tract, renal system, and occasionally the central nervous system.