RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164078270 T1 Melkersson-Rosenthal Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164078270 RD 2024/04/23 AB It is a disorder characterized by recurring facial paralysis associated with cheilitis (chronic swelling of the face), and lingua plicata (“scrotal” tongue). The tongue is often hypertrophic and macroglossic. Granulomatous cheilitis is a chronic swelling of the face and lips, especially the upper lip that is caused by granulomatous inflammation. The onset of the disease begins in childhood or early adolescence. After recurrent attacks that can last days to years in between, the swelling may persist, increase, and eventually become permanent. Miescher cheilitis is the term used when the granulomatous changes are confined to the lip. Miescher cheilitis generally is regarded as a monosymptomatic form of the Melkersson-Rosenthal Syndrome, although the possibility remains that they are separate diseases. It is believed symptomatic of Crohn’s disease and sarcoidosis.