RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164076600 T1 Lennox-Gastaut Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164076600 RD 2024/03/28 AB It is a severe childhood onset form of intractable epilepsy that begins between the second and sixth year of life. Classically, it is defined by a triad of clinical signs consisting of severe learning disabilities, frequent seizure activities, and an EEG recording characterized by less than 2.5 Hz slow pike wave recording. Daily multiple seizures are typical and the most frequent type of seizures is myotonic and occurring 90% during the night. The second most frequent presentation is myoclonic seizures triggered when the patient is physically exhausted. It is associated with a poor prognosis in childhood. Five percent of patients die within 10 years from the onset of the disease.