RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164076303 T1 Laron Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164076303 RD 2024/11/01 AB It is a genetically transmitted endocrine disorder characterized by severe dwarfism. It is associated with a congenital insensitivity to growth hormone (GH). Besides dwarfism, the clinical features include a blue sclerae, hip degeneration, prominent forehead, depressed nasal bridge, micrognathia, truncal obesity, and micropenis. Females have normal sexual character development. Acute hypoglycemia and seizures are often present. As a matter of interest, it was reported in 2011 that individuals affected with this medical condition in Ecuador are resistant to cancer, diabetes mellitus, and to an extent protected against aging.