RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164073107
T1 Homocystinuria (HCU)
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164073107
RD 2023/03/29
AB Genetically  transmitted  error  of  metabolism  of  the  amino  acid  methionine  leading  to  a  multisystemic  disorder  of  the  connective  tissue,  muscles,  central  nervous  system,  and  cardiovascular  system.  It  is  characterized  by  severe  myopia,  Marfan-like  stature  with  pectus  excavatum,  slight  mental  retardation,  and  tendency  to  develop  spontaneous,  generalized  arterial,  and  venous  thromboses  under  stress.  A  special  consideration  must  be  given  to  anesthesiologists  using  nitrous  oxide  during  anesthesia.  An  association  between  its  administration  and  the  potential  risk  for  an  acute  and  severe  thromboembolism  syndrome  must  be  taken  into  consideration.