RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164072658 T1 Hereditary Sensory and Autonomic Neuropathy Type I (HSAN I) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164072658 RD 2024/03/29 AB Genetic neurodegenerative disorder characterized by a loss of sensations, especially in the lower extremities, leading to perforating skin ulceration and bone destruction as a result of abnormal functioning of the autonomic nervous system. Type I is the most common form among the five types of HSAN. The disease usually starts during early adolescence or adulthood. The disease is characterized by the loss of pain sensation mainly in the distal parts of the lower limbs such as feet and lower legs.