RT Book, Section
A1 Bissonnette, Bruno
A1 Luginbuehl, Igor
A1 Engelhardt, Thomas
SR Print(0)
ID 1164072450
T1 Hemophilia B
T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781259861789
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164072450
RD 2024/04/16
AB Hereditary  coagulation  disorder  caused  by  defective  synthesis  of  plasma  protein  factor  IX.  It  is  the  second-most  common  form  of  hemophilia,  rarer  than  hemophilia  A.  The  clinical  hallmark  of  hemophilia  B  is  articular  hemorrhage.  This  bleeding  is  painful  and  leads  to  long-term  inflammation  and  deterioration  of  the  articulation.  It  is  typically  present  in  children  and  affects  the  ankles,  whereas  it  more  often  involves  the  knees  and  elbows  in  adolescents  and  adults.  These  complications  results  in  permanent  articular  deformities,  misalignment,  loss  of  mobility,  and  lead  to  extremities  of  unequal  lengths.