RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164072422 T1 Hemophilia A T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164072422 RD 2024/10/09 AB Most severe hereditary coagulation disorder. It is caused by defective synthesis of plasma protein factor VIII. The condition must be suspected in the presence of prolonged bleeding following a venepuncture or simple heel prick at the time of birth.