RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164072081 T1 Happy Puppet Syndrome T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164072081 RD 2024/03/29 AB The Happy Puppet Syndrome (Angelman’s Syndrome) is a genetic disorder that mainly affects the nervous system. The clinical features include microcephaly, happy facial appearance, severe mental retardation, developmental disability, speech problems (absence of speech), balance and movement problems, seizures, and sleep problems and social disposition. Children are usually happy in nature and have a particular interest in water. The symptoms generally become noticeable by 1 year of age.