RT Book, Section A1 Bissonnette, Bruno A1 Luginbuehl, Igor A1 Engelhardt, Thomas SR Print(0) ID 1164070933 T1 Glutaric Acidemia Type I (GA-I) T2 Syndromes: Rapid Recognition and Perioperative Implications, 2e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781259861789 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1164070933 RD 2024/12/05 AB Progressive inherited neurologic disorder caused by a genetically transmitted inborn error of metabolism leading to break down completely the amino acids lysine, hydroxylysine and tryptophan. Excessive levels of their intermediate breakdown products, ie, glutaric acid, glutaryl-CoA, 3-hydroxyglutaric acid, and glutaconic acid can accumulate and cause damage to the brain. The basal ganglias are most often affected which may cause neurological irregular movement. Mental retardation may occur.