RT Book, Section A1 Hess, Dean R. A1 Kacmarek, Robert M. SR Print(0) ID 1157418342 T1 Ventilator-Induced Lung Injury T2 Essentials of Mechanical Ventilation, 4e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260026092 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1157418342 RD 2023/03/20 AB Discuss the primary factors that contribute to ventilator-induced lung injury (VILI).Discuss stress and strain as related to lung injury.Describe mechanisms whereby small tidal volumes and positive end-expiratory pressure (PEEP) modify the risk for VILI.Discuss the impact of double triggering on the development of VILI.Discuss the effect of an inappropriate ventilatory pattern on inflammatory mediator response and the translocation of cells and molecules.Describe the relationship between VILI and multiple organ dysfunction syndrome (MODS).Discuss the clinical outcomes data to support the use of lung-protective ventilatory strategies.