RT Book, Section A1 Hess, Dean R. A1 Kacmarek, Robert M. SR Print(0) ID 1157418259 T1 Physiologic Effects of Mechanical Ventilation T2 Essentials of Mechanical Ventilation, 4e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260026092 LK accessanesthesiology.mhmedical.com/content.aspx?aid=1157418259 RD 2024/04/23 AB Compare intrathoracic pressure during spontaneous breathing and positive-pressure ventilation.Describe the effects of positive-pressure ventilation on shunt and dead space.Discuss the roles of alveolar overdistention and opening/closing on ventilator-induced lung injury.Discuss the physiologic effects of positive-pressure ventilation on pulmonary, cardiac, renal, gastrointestinal, and neuromuscular function.Describe the effects of sedation and delirium in the mechanically ventilated patient.Discuss the effects of positive-pressure ventilation on nutrition, the upper airway, and sleep.Describe methods that can be used to minimize the harmful effects of positive-pressure ventilation.