RT Book, Section
A1 Teplick, Richard
A1 Calderon, Eduardo
A1 Kelley Tyler, Shannon
A1 Vande Waa, John
A2 Longnecker, David E.
A2 Mackey, Sean C.
A2 Newman, Mark F.
A2 Sandberg, Warren S.
A2 Zapol, Warren M.
SR Print(0)
ID 1144113809
T1 Principles of Antimicrobial Therapy
T2 Anesthesiology, 3e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071848817
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1144113809
RD 2023/12/06
AB KEY  POINTSAntimicrobial  therapy  should  be  based  on  infection  site,  host  defenses,  antibiotic  pharmacokinetics  and  pharmacodynamics,  and  local  microbial  susceptibility  patterns.Antibiotic  use,  especially  of  broad-spectrum  drugs,  is  often  inappropriate  and  may  lead  to  microbial  resistance.  The  Centers  for  Disease  Control  and  Prevention  (CDC)  encourage  the  development  of  formal  antibiotic  stewardship  programs  to  encourage  the  judicious  use  of  antibiotics  and  minimize  adverse  events.The  term  catheter-associated  infection,  which  indirectly  associates  a  bloodstream  infection  with  the  current  or  recent  presence  of  a  catheter,  is  designed  for  surveillance,  whereas  a  catheter-related  bloodstream  infection  is  directly  attributable  to  a  catheter.The  optimal  location  to  avoid  a  catheter-related  infection  is  controversial,  although  most  data  favor  subclavian  placement.  In  hospitalized  patients,  peripherally  inserted  central  catheter  (PICC)  lines  have  infection  rates  similar  to  those  for  central  catheter  placement  in  other  locations.Bacteria  causing  ventilator-associated  pneumonia  are  similar  to  those  in  other  hospitalized  patients.  The  efficacy  of  “bundles”  for  their  prevention  is  controversial.Prophylactic  antibiotics  for  surgery  should  be  administered  for  all  clean-contaminated  and  contaminated  wounds  as  well  as  for  hysterectomies  and  most  invasive  urologic  procedures.  With  a  few  exceptions,  they  should  be  discontinued  within  24  hours.