RT Book, Section
A1 De Oliveira, Gildasio S.
A1 Benzon, Honorio T.
A1 White, Paul F.
A2 Hadzic, Admir
SR Print(0)
ID 1141738470
T1 The Role of Nonopioid Analgesic Infusions in the Management of Postoperative Pain
T2 Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071717595
LK accessanesthesiology.mhmedical.com/content.aspx?aid=1141738470
RD 2024/04/25
AB Opioids  are  the  most  commonly  used  medications  for  perioperative  pain  control.  However,  opioid-related  side  effects  such  as  constipation,  nausea,  vomiting,  and  respiratory  depression  often  accompany  the  use  opioids.  Many  studies  have  evaluated  the  efficacy  of  nonopioids  such  as  ketamine,  lidocaine,  naloxone,  and  magnesium  as  perioperative  infusions  to  decrease  postoperative  pain  and  minimize  the  use  of  opioids  after  surgery.  Infusions  of  the  short-acting  beta-blocker  esmolol  and  the  α2  agonist  dexmedetomidine  have  also  been  investigated  as  adjuvants  to  reduce  the  postoperative  opioid  requirement.  In  this  chapter,  the  results  of  the  studies  on  infusions  of  ketamine,  lidocaine,  naloxone,  esmolol,  α2  agonists,  and  magnesium  will  be  summarized,  and  recommendations  on  their  clinical  applicability  as  part  of  perioperative  pain  management  will  be  made.